Sodium Stearate

Sodium stearate is produced as a major component of soap upon saponification of oils and fats. Purified sodium stearate can be made by neutralizing stearic acid with sodium hydroxide.

Product Description

About Sodium stearate

Sodium stearate or sodium octadecanoate, is the sodium salt of stearic acid. It is the major component of some types of soap. It is present in many types of solid deodorants, rubbers, latex paints, inks and accelerators. It is also a component of some food additives and food flavorings. In addition, It is also used in the pharmaceutical industry as a surfactant, to aid the solubility of hydrophobic compounds in the production of various oral dosage forms. It does this due to the molecule having both hydrophilic and hydrophobic nature. Sodium stearate molecules can form micelles, presenting their hydrophilic heads outwards and their hydrophobic tails inwards, providing a lipophilic environment for hydrophobic compounds to exist in.

References on Sodium Stearate

[1]. Lu H, Hao L, Li S, Lin S, Lv L, Chen Y, Cui H, Zi T, Chu X, Na L, Sun C. Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway. Diabetologia. 2016 Mar 11.

[2]. Ma F, Chen S, Liu P, Geng F, Li W, Liu X, He D, Pan D. Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. Mater Sci Eng C Mater Biol Appl. 2016 May 1;62:407-13.

[3]. Ma Y, He S, Ma X, Hong T, Li Z, Park K, Wang W. Silymarin-Loaded Nanoparticles Based on Stearic Acid-Modified Bletilla striata Polysaccharide for Hepatic Targeting. Molecules. 2016 Feb 29;21(3). pii: E265.

[4]. Mosquera-Restrepo SF, Caro AC, Peláez-Jaramillo CA, Rojas M. Mononuclear phagocyte accumulates a stearic acid derivative during differentiation into macrophages. Effects of stearic acid on macrophage differentiation and Mycobacterium tuberculosis control. Cell Immunol. 2016 Feb 26. pii: S0008-8749(16)30009-0.