L-Glutamic Acid

L-Glutamic Acid, CAS# 56-86-0, is one of many non-essential amino acids that are produced in the body. Downstream derivatives of L-glutamic acid include salts and carboxylate anions, also known as glutamates. Glutamates and other L-glutamic acid derivatives are used in foods, flavorings, nutritional supplements and pharmaceutical products.

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Product Description

About L-Glutamic Acid

L-Glutamic acid occurs naturally in many protein-rich foods and is typically used as a flavoring agent when added to food products in its crystalline salt state, Monosodium Glutamate-MSG. Although L-glutamic acid is naturally present in numerous foods that contain protein, it cannot be tasted in these foods unless it is unbound (i.e. not part of a long protein chain). In its unbound form, L-glutamic acid is gives off the taste known as umami, which is a rich and savory flavor tasted at the back of the tongue.

L-Glutamic acid is a member of the amino acids chemical family, and amino acids are the building blocks of proteins. Long protein chains typically comprise several different amino acids, and each type of amino acid has different properties and effects. Many amino acids are essential amino acids, meaning that they are not produced in the body and must be obtained from other sources (protein-rich foods are sources of essential amino acids). L-glutamic acid is a non-essential amino acid because it is produced naturally in the body.

References on L-Glutamic Acid

[1]. Skibinska I, Tomaszewski M, Andrusiewicz M, Urbaniak P, Czarnecka-Klos R, Shadi M, Kotwicki T, Kotwicka M. Expression of Estrogen Receptor Coactivator Proline-, Glutamic Acid- and Leucine-Rich Protein 1 within Paraspinal Muscles in Adolescents with Idiopathic Scoliosis. PLoS One. 2016 Apr 5;11(4):e0152286.

[2]. Gao LJ, De Jonghe S, Daelemans D, Herdewijn P. l-Aspartic and l-glutamic acid ester-based ProTides of anticancer nucleosides: Synthesis and antitumoral evaluation. Bioorg Med Chem Lett. 2016 Mar 22. pii: S0960-894X(16)30307-9.

[3]. Qi H, Coplen TB, Mroczkowski SJ, Brand WA, Brandes L, Geilmann H, Schimmelmann A. A new organic reference material, l-glutamic acid, USGS41a, for δ(13) C and δ(15) N measurements - a replacement for USGS41. Rapid Commun Mass Spectrom. 2016 Apr 15;30(7):859-66.

[4]. Perdomo D, Manich M, Syan S, Olivo-Marin JC, Dufour AC, Guillén N. Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica. Cell Microbiol. 2016 Feb 9.